Wednesday, January 8, 2020

Television And Its Impact On Children - 1309 Words

Television has stood in a unique technological position throughout its history. Largely coming to the American public in the post-WWII era, this strange new device quickly became controversial. There were worries centered on how much time children spent watching it or what morals programs were imbuing in their young viewers. In later years, while these concerns continued, and perhaps grew to had a validity to them, others joined them as televised programs grew graphic and polarized. Forensic television showed bloody murders in action and networks advertised their gore and nudity as a positive. On the less fictional side of the small screen, the 24-hours news cycle began and sensationalized opinions exploded. Faced with a rapid degree of transformation from their own childhoods to the present, people found themselves asking if modern television was having negative repercussions on adults as well. And amidst the ongoing conflict with content, commercials rose and with them ideas that p hysical products would lead to a higher quality of life. While some concerns might be undeserved, what we consume affects us. We are being manipulated in a variety of ways and the consequences are not pleasant. That people find television enjoyable is reasonable. Some of the shows currently available stand as thought-provoking and among the best to exist. And even if the rest lack such traits, condemning entertainment for being without sufficient cerebral qualities is enough to drag the dreadedShow MoreRelatedTelevision And Its Impact On Children s Lifestyle1742 Words   |  7 Pagesinternet coverage, increased radio frequencies, and digital television coverage. Given the relatively cheap but wide coverage and in depth analysis of news and other programs, uses of television continue to rise. High numbers of populations enjoy wide television coverage at low cost. Due to this reason, the prevalence of television as a news and lifestyle programmer in the society continues to rise. Inc reasing the society’s access to television services is an important factor in developing educationalRead MoreEssay on How Television Impacts our Children1123 Words   |  5 PagesTelevision has been around for over a half century. The first view of TV in the United States took place at a Worlds Fair in 1939, but standard television broadcasting did not begin until the late 1940s. Worry about the influence of television on children began when TV was in its early years. Early on in the 1950s, educators and parents began to ask legislators to do something about the amount of violence on TV. This concern still exists today. Parents have reservations about the quality of televisionRead MoreDoes Violence On Television Really Impact Children?1469 Words   |  6 Pages Does violence on television really impact children? A lot of media claim TV violence does by correlating it with aggression, which is why there are many advertised parental locks, mostly by television cable companies . Parents cannot always be there whenever children witness something violent on television. Thus, we studied how often violent acts actually appeared on two types of television shows children may possibly watch. In our study, we chose to watch an adult drama, The Walking Dead, whichRead MoreEssay about Effect of Television Viewing on Child Development952 Words   |  4 PagesGrace Nowadays, television has been played a major role in most family households. Although television was invented over half a century ago, it has now become a part of most children’s everyday lives. Children have begun to turn to television for their main source of entertainment .Television has its own good sides but research shows that the disadvantages of television watching for children outweigh the advantages. This is because it will affect children’s health, children’s educationalRead MoreImpact of Cartoons on Children766 Words   |  4 PagesImpact of Cartoons on Children Indraprastha College for Women Bachelor in Mass Media and Mass Communication 4th semester 2nd year 2010-11 Anisha Tandon Introduction â€Å"A child s life is like a piece of paper on which everyone who passes by leaves an impression.† - Chinese Proverb Children are often considered to be the closest reflection of the omnipotent creator of the world. Innocence and purity personified, they are unmarred by the corrupt thoughts and practices. They resembleRead MoreEffects of Television on Child Development: Comparing Adverse and Positive Consequences of Watching Television1138 Words   |  5 PagesEffects of Television on Child Development: Comparing Adverse and Positive Consequences of Watching Television Studying the effects of children watching television has been a popular field of research for many years and is becoming increasingly important as more of children’s time is spent on television. There are strong arguments for both the benefits and the detriments of television exposure. One of the most common arguments against television is the suggestion that it increases violence. OtherRead MoreThe Effect Of Television Exposure On The Behavior Of Infants Or Children1353 Words   |  6 PagesThe impact of television exposure is relatively unknown in the recent decades. Therefore, large number of studies has been considered in order to find out the impact of television exposure on the behaviour of infants or children. According to the classic studies conducted by Bandura et. al (1963), the 3 to 5 years children continuously observe the aggressive behaviour of adult. Then they carry out the same aggressive behaviour in front of children, doll or other toys. Consequently, children imitateRead MoreReality Television Has A Negative Impact On Society981 Words   |  4 PagesAs a kind of television programming which has lower production fee and a larger range of audiences,reality television has become a major force of television entertainment.It changes the way audiences watch television by providing imaginary space for them,allowing them fantasize themselves as the part of the show(Hicks,2009).However,while the reality television is argued as ‘highly edited reality’,the positive effects are doubted by some observers.The reality television in this essay can be definedRead MoreThe Negative Effects of Television on Children in Society Essay1308 Words   |  6 PagesAn estimated one billion television sets have been sold in North America, and on average, children watch 28 hours per week. The effect of television creates negative development in children. Television is one of the biggest contributions to the growing amount of obe se children in North America. The amount of glorified violence in today’s society can be attributed to children watching high rated television shows. Many young children are involved in promiscuous behaviour. This might be a result ofRead MoreEffects Of Children s Television On Language Development Essay1487 Words   |  6 Pagesand Co. reported that children between the ages of two and five watched television on average 32 hours a week - an eight year high. Parents’ opinions on their children’s television viewing has contributed to this upward trend. In 2014, the Joan Ganz Cooney Center surveyed 1,557 parents of children between the ages of 2 and 10; they found that 44% of parents believed that children’s television enhanced learning. In addition, the center reported that 78% of parents of children between the ages of two

Tuesday, December 31, 2019

Analysis Of The Article Fences - 1165 Words

Fences by August Wilson is a play about an African-American family in the 1950s. Troy Maxson is the breadwinner of his entire family because of his job in a garbage truck company. Cory, one of the children of Troy, is a great football player in high school and he wants to continue to play for college football, which has been absolutely denied by Troy because of the discrimination as a colored people they have. Rose, Troy’s wife, who is taking care of everything at home, but lost her love for Troy when she knew that Troy has been seeing some other woman. Fences happened in the 1950s, a period that is full of the social position in the African-Americans’ struggling and changing for survival. In the article â€Å"Baseball as History and Myth in August Wilson’s Fences† by Koprince Susan, a professor of English at the University of North Dakota. She expounds that â€Å"The game of baseball has long been regarded as a metaphor for the American dream — an expression of hope, democratic values, and the drive for individual success.† In the play, Troy complained to his boss about why black employees aren’t allowed to be the garbage truck driver. Later on, after the conversation with Mr. Rand, his boss, and the Commissioner of the union, Troy got a promotion to be the garbage truck driver. This is a perfect example of what Ms. Koprince stands for. The social attitude of colored people is changing and developing. The baseball is a symbolic representative of how the African American is sufferingShow MoreRelatedCharacter Analysis of Cory in The Play Fences by August Wilson1109 Words   |  5 Pagesbecause of a fear that was rooted in him nearly eight-teen years earlier. When Troy was released from prison he dreamed of playing Major League Baseball but at that time it was an impossibility because of racial dis he other primary relationship of Fences is that of Troy to his son Cory (Courtney B. Vance) - a promising 17-year-old football player being courted by a college recruiter. Troy himself was once a baseball player in the Negro Leagues - early enough to hit homers off Satchel Paige, tooRead MoreBreak Even Analysis1227 Words   |  5 PagesBreak Even Analysis In business planning, asking the proper questions and obtaining answers to those questions is arguably the most important thing. Questions such as; how much do we have to sell to reach our profit goal? How much do our sales need to increase in order to cover a planned increase in advertising costs? What price should we charge to cover our costs and allow for the planned profit goals? Is our business going to be profitable? Answers to such difficult questions become accessibleRead MoreThe Importance Of Innocence In Wendy Copes Reading Scheme1245 Words   |  5 Pagesof innocence in Wendy Cope’s poem we will first familiarize ourselves on the topic of innocence by looking at two different articles to aid our argument. Also, we will recognize Cope’s writing style and its connection to the theme of the poem. Finally, we will analysis Cope’s poem by looking at evidence from the poem and the perfect villanelle form. According to the article Archaeology: the loss of innocence, written by David Clarke â€Å"the loss of disciplinary innocence is the price of expanding consciousness†¦theRead MoreThe Problem Of Social Cost1117 Words   |  5 PagesProblem of Social Cost The Problem of Social Cost by R.H. Coast is an article examining the economic problem of externalities. The example of externality is a firm’s smoke imposed negative effects on neighbor properties. The standard economic analysis such of the economic situation is generally defined in differences terms of private and social good followed by the treatment of Pigou Economic Welfare. The standard economic analysis results in achieving most of the economists desires to hold firms responsibleRead MoreNotes On The Novel Fences And Pied Piper Of Tucson 1080 Words   |  5 Pagesreading of Joyce Carol Oates’ short story, â€Å"Where Are You Going, Where Have You Been?† and Mara Bovsun’s article, â€Å"Pied Piper of Tucson;† they identify and describe ways authors ‘hook and hold’ readers with specific choices. Next, students read the play Fences by Pulitzer Prize winner August Wilson and analyze the role of stories within in the story to create tension and advance the plot. Fences is the foundation for the unit’s cornerstone task: after ranking and discussing important lines in theRead MoreSymbolic Source In A Worn Path by Eudora Welty1287 Words   |  6 Pagesthan a century. In an article titled â€Å"’A Worn Path’ Analysis† the author declares â€Å"Phoenix bird has a cycle of life, death, and rebirth†. In the story â€Å"A Worn Path†, Eudora Welty describes Phoenix Jackson as an â€Å"old Negro woman† (Welty1274). Endurance also represents Phoenix because even though she struggles to get his grandsons medicine, she still manages to go through the woods to the town and back to her house just to get his medicine. In the article â€Å"‘A Worn Path’ Analysis†, â€Å"she falls, gets backRead MoreA Research Into The Enteric Nervous System995 Words   |  4 Pages This system, born in the embryonic stage as part of the neural crest and then migrate to what becomes our intestines, they theorize reacts sympathetically to the food we ingest and its own flora and thereby influence our mood and emotions. The article cites several studies both with people and mice that demonstrated some connection between the food that was consumed and emotion. In some case the food seemed to trigger some emotions and in others emotions caused the subjects to gravitate to certainRead MoreAnalysis Of The Statue Of Marshal Ney In The Fog1368 Words   |  6 Pageselement, a monument representing the i llustrious French military commander Michel Ney (which gives the title to the entire work), positioned on the extreme left, dominating the mid and upper third, while in the lower one it is possible to notice a round fence that encircles the statue, creating both a physical and ideal perimeter around the statue. The right side of the picture is occupied by thick grey brume that occults what could be present in the square, apart from two items. One of them is almost indecipherable:Read MoreFraud Management : An Architectural Insight1144 Words   |  5 Pagesrush to secure the Holy Grail from reaching the fraudsters also causes a high for a broader section of the ethical technical audience who strive to ring fence their organizations. It is quite a feat to think through the various loop holes to ensure that no repeatable fraudulent pattern is left un-scrutinized. An attempt has been made in this article to address available technologies to fend off Fraudsters, and the architectural in sight needed from an enterprise technical architecture standpoint. TypesRead More`` Exquisite Corpse `` By Ashraf Rushdy951 Words   |  4 PagesTransition published a journal article in 1999, Issue 83 (Volume 9, Number 3) â€Å"Exquisite corpse†, written by Ashraf Rushdy. This article chronicled numerous hate crimes executed against African Americans by Caucasians as far back as 1933. The Transition article, a journal dedicated to the advancement of the African American community, written by Rushdy, look to reduce the propensity and likelihood of their constituents being lynched by the white community. It is Rushdy’s hypothesis that prominently

Sunday, December 22, 2019

Organizational Behavior Apple And Samsung - 1922 Words

Organizational Behavior Apple Samsung Student Name : Mengting KE Tutor Name : Vinay Reddy Subject : Organizational Behavior Word account: Contents Introduction ———————————————————————————————— 3 - 4 different approaches to management and leadership —————————————— 5 - 6 Apple’s approaches to management and leadership —————————————— 6 - 7 Samsung’s approaches to management and leadership ————————————— 7 Comparison ———————————————————————————————— 8 Ways of using motivational theory in organizations ——————————————— 8 - 9 Developing effective teamwork ——————————————————————— 10 - 1 Conclusion ———————————————————————————————— 11 Reference List ——————————————————————————————12 - 13 Introduction As a consultant for Orb Ltd a company who specializes in organizational behavior. I have been asked by the CEO to research areas within organizational behavior on the two examples that I selected, so it can be used for future training. Organizational behavior (OB) is the study of the way people interact within groups. Normally this study is applied in an attempt to create more efficient business organizations.(Investopedia.com 2010) Another definition for OB is an action and attitudes of individuals and groups toward one another and toward the organization as a whole, and its effect on the organization s functioning and performance.(WebFinance 2016b) The two companies I have choices are Apple and Samsung. As a well-know companies, Apple and Samsung couldShow MoreRelatedBus 599 Week 10 Assignment 4: Capstone Project Strategic Management628 Words   |  3 Pagesrategic-management/ BUS 599 Week 10 strategic management of Apple Inc. and Samsung Group. Due Week 10 and worth 480 points Use the Internet or the Library to research articles on strategic management of Apple Inc. and Samsung Group. Write a ten to twelve (10-12) page paper in which you: Analyze the existing business strategies, domestic and global environments, industry, and internal capabilities for both Apple and Samsung. Assess the significant manner in which each company’s mission andRead MoreThe Marketing Of Apple Incorporated Essay1406 Words   |  6 Pages Steve Jobs, Steve Wozniak, and several others founded Apple Incorporated in 1976 because they had a passion for developing computers (Yoffie Rossano, 2012). The computers were meant to be user-friendly so that any person could use the computers with ease. Apple’s focus is on continuing to find new ranges of products concerning laptops phones, and many other products. During the making of their computers, the company found that bundling the hardware and software the company produced the Mac OperatingRead MoreWada1669 Words   |  7 PagesDiagnosing the Change Managing Organizational Change Emiliano Delucia Keller Graduate School of Management DIAGNOSTIC MODELS One of the main purposes of diagnostic models is to find a way to identify external and internal factors that can affect the working conditions of an organization. Many diagnostic models have been developed along the years to ensure these factors are well identified and the organizations can function properly following a certain model. The diagnostic modelRead MoreManagement and Organizational Culture in Samsung1548 Words   |  7 PagesCourse: NZDB 530 Organisation and Management Trimester 2 2010 Assessment 2: Essay on Organizational Culture SAMSUNG ELECTRONICS Submitted by: Chung Daewan(Steve) ID# 20904451 Submitted on: 5th July 2010 Submitted to: Jene Parilla TABLE OF CONTENTS â…  . Essay on Organizational Culture †¦Ã¢â‚¬ ¦..................................................3 â… ¡. Metaphor†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.......................................................................................6 â… ¢. Appendices†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..................................Read MoreManagement and Organizational Culture in Samsung1541 Words   |  7 PagesCourse: NZDB 530 Organisation and Management Trimester 2 2010 Assessment 2: Essay on Organizational Culture SAMSUNG ELECTRONICS Submitted by: Chung Daewan(Steve) ID# 20904451 Submitted on: 5th July 2010 Submitted to: Jene Parilla TABLE OF CONTENTS â…  . Essay on Organizational Culture †¦Ã¢â‚¬ ¦..................................................3 â… ¡. Metaphor†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.......................................................................................6 â… ¢. Appendices†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...................Read MoreStrategic Management Of Apple Inc. And Samsung Group2547 Words   |  11 PagesManagement of Apple Inc. and Samsung Group Analyze Apple and Samsung domestic and global environments, industry, internal capabilities, mission and vision. Apple and Samsung, actually, considered as pioneers in technological industry. Every company has chosen different business strategies and models within the marketplace. Apple releases few but highly anticipated high-end products while Samsung inundates the market with a wide variety of products. In the beginning, Apple was very carefulRead MoreOrganisational Behaviour4667 Words   |  19 PagesOrganizational Behavior Stimulating Forces To Differentiate Planned From Unplanned Change Apple‟s soon to be legacy... Page 1 Organizational Behavior Table Of Content Introduction page 3 Company Background Operational Definition page 4 Current Scenario page 5 Apple and Steve Jobs Current Position of Apple Smartphone Industry Trends page 6 Force Field Analysis page 7 Kurt Lewin‟s Model page 8 Criticism of Lewin‟s 3-Step Model page 12 Conclusion Read MoreManagerial Economics And Management Decisions By C. M. Birch1702 Words   |  7 Pagesthe case of Samsung, many of these global factors played a substantial role in deciding the survivability rate of the company from succeeding or declaring bankruptcy. This paper will serve as a means to understand Samsung’s corporate orientation such as culture, strategy, structure, organizational leadership, ethical programs, and associated risks. In addition, to analyzing past decisions and identify new strategies to improve Samsung’s corporate function. The South Korean giant, Samsung, is knownRead MoreAnalysis Of Apple And Samsungs Business Strategies Essay2053 Words   |  9 PagesAnalytical perspective of both apple and samsungs’ business strategies Apple Inc. (Apple), headquartered in Cupertino, California, has become a household name around the globe. The company’s business strategy is to bring the best personal computing, portable digital music and mobile communication experience to not only consumers but to students, educators, businesses, and government agencies alike (Appel, 2014). Apple accomplishes this through innovative hardware, software, peripheral, internetRead MoreA Porter 5 Forces Industry Analysis1476 Words   |  6 Pages1] Do a Porter 5 Forces Industry analysis of the PC Industry (NOT just Apple but the Industry as a whole) 2] Historically, what have been Apple’s competitive advantages? 1970 to 1980 an area where technology started to become a filed for competition Steve Jobs and Steve Wozniak in 1976 innovated the first Apple machine and in that year a new generation of computers brand production was borne. Apple’s history is considered an inspiring maze for many who are willing to become a leader in an industry

Saturday, December 14, 2019

Use of Chemical Weapons and its Effects on the Neighboring Countries Free Essays

Globalization can be defined as the process of integrating the social, economic, political, and cultural of different countries globally. Globalization stems back all the way to the second half of the 20th century. Globalization has plenty of accolades, but it also has major negative consequences. We will write a custom essay sample on Use of Chemical Weapons and its Effects on the Neighboring Countries or any similar topic only for you Order Now Scientific developments hastened with globalization and tools of mass destruction like chemical weapons started being produced on large scale and demand. This paper focuses on how the use of chemical weapons in Syria has affected the Syrian environment and its relations with its neighboring countries. Background Chemical weapons are some of the most dangerous tools to be used in war. Chemical weapons have been used for centuries in fight, but it was not until the First World War that they were used in large scale. According to Ahmet ÃÅ"zà ¼mcà ¼ says that this was all made possible by the rapid advances in science technology that enabled the mass production of these lethal weapons. Despite the early efforts to control the use of these weapons by signing the Geneva protocol in 1925, it did not require that one could not stock chemical agent; therefore, they continued to be used in warfare during the cold war and even the Iran-Iraq war. In 1993, the world community signed the chemical weapon convention, which was enforced in 1997 (1). This was a much comprehensive ban on chemical weapons. Destruction of these weapons is projected to conclude in the next few years. Recent events in Syria have reminded the world of the horrific impact of chemical weapons. According to Pita Renà © and Juan Domingo, the Syrian government accused a terrorist group of firing a chemical rocket at the southeast of the city of Aleppo, Khan Al Asal that took the lives of 25 innocent people and injured more than 110 people (2). Jefferson quoted the US secretary of state on the event as â€Å"moral obscenity†. The Organization for the Prohibition of Chemical Weapons (OPCW) could not investigate the disaster since at the time Syria was not a member of the Chemical World Convention. However, after the Syrian Government asked the United Nations to investigate whether the use of chemical weapons caused the attack, it started the UN Secretary-General Mechanism (SGM). The UN Secretary-General assembled a mission that consisted of OCPW personnel and medical staff from the world health organization (4). The investigation did confirm that the attack was chemical based, and also set the base for the investigation of other alleged chemical weapon attacks with France and the United Kingdom accusing Syria of another chemical related attack. These were followed by other allegations by Qatar and the USA. They were all alleging that through their investigations they had found the 12 different attacks to have been caused by chemical weapons which were in possession of the Syrian government. The investigations were conducted through the means of individualized governments, which meant that the UN could not use the findings. The United Nations could not use these findings because they did not have the proper chain of protection, as the United Nations required the investigation to be done by its personnel. However, after all the turn of events, the Syrian government decided to join the CWC led to the commencement of international efforts to completely Syria of these dangerous chemical weapons (5). Problems The use of Chemical weapons in Syria attracted a lot of attention from big world powers. Greg says that the USA and the UK became the most spoken in the fight against removing chemical weapons and a new regime in Syria. After the statement of the US secretary of state John Kerry, the then President of the United States of America Barrack Obama also issued a statement warning Syria that any use of chemical weapons by the country would be crossing a global red line. The British Prime minister David Cameron despite conceding the parliamentary vote on taking part in military action and gave a striking warning that the use of chemical weapons would quality a strong response from the United Kingdom. According to Christian Henderson, the UK decided that by â€Å"legal basis military action would be humanitarian intervention.† Syria had potentially made unnecessary powerful enemies who could subdue it if it went past diplomacy (3). Syria was not part of the CWC when the first attack took place; this meant that the relevant authority that was assigned with the task of investigating chemical attacks could not get involved. Even though other individualized governments had carried out their investigation due to the lack of chain of custody of the investigations, even the UN could not take any action. This meant the process would drag on for a longer period than it should have and the relationship between the countries involved would continue to strain. In turn, the process of ridding the universe of chemical weapons would suffer setbacks. Pros The attack in Syria brought back the attention of the world to a problem that needed an urgent solution. Syria was still one of the countries that were still not in the CWC, and the attack showed the world that they needed to do everything possible to get the other countries to join CWC. According to Catherine Jefferson, Syria did allow and joined CWC and had since cooperated with the body in the destruction of the chemical weapons stock. For the OPCW to get involved in the first investigation, it required the activation of the SGM, the enactment of this mechanism showed the importance of achieving Universal membership (2). Since Syria became part of the CWC actions have been taken to ensure that Syria destroys the chemical weapons and through this Samiotis and Grekos, shows in 2014 chemical weapons from Syria were destroyed aboard a vessel belonging to the US Maritime Administration by the name MV Cape Ray in the Mediterranean Sea. This was a big milestone in the fight for a world free from chemical weaponry (2). Cons The first agreement against chemical weapons, the Geneva protocol was signed in 1925, but countries were still stockpiling chemical weapons, and it took well over 68 years before the Chemical Weapon Convention was established in 1993. It took another four years for it to be enforced, but the drawback is that there are countries that are not part of the CWC; thus, this does not affect that which puts the convention under threat. This is seen when the attacks in Syria take place by the use of the weapons, and it is even harder to assemble a mission to investigate the attacks due to the lack of custody (Renà © and Domingo 2). The convention has played a big role in destroying chemical weapons, but there is still a long way to go before they accomplish this mission entirely. The use of chemical weapons in Syria has a very negative effect on the natural environment of the countries affected. According to Pita Renà © and Juan Domingo shows, that the samples collected from the scene of the attack had Sarin decomposition and metabolites. The destruction of chemical weapons in the Mediterranean Sea according to has consequences that even from a scientific perspective still do not know the extent to which it may destroy the sea. The chemicals involved in the making of the weapons cause a lot of damage to the environment which if not dealt with my cause a permanent problem. Many of the attacks have happened within Syria, and any signs of way are a threat to political stability and attainment of world peace. The claims that have been made against the Syrian government have not been proven, and thus no one has taken responsibility for the attacks (4). Solutions According to Christopher Jenkins, the CWC is on the right track towards the complete destruction of chemical weapons. The CWC should engage the countries that have not joined them to subscribe to the cause and help the world become chemical weapon free. Most of the countries are storing the weapons because of the uncertainty that they might face a war shortly. If the CWC and other relevant authorities come together, get involved and guarantee these countries that they won’t fall into the attack, then it may be possible to get them to join CWC (1). Recommendations The Syrian government has strained relations with other countries due to the recent attacks. It is important for these countries to have a good international relationship for the CWC to be well enforced and reduce any chances of them getting into a war and spark another wave of large-scale production chemical weapons. The Syrian government should also get involved in the process of restoring the country to a more stable state. They should get as much outside help as possible and enhance their international relationships. How to cite Use of Chemical Weapons and its Effects on the Neighboring Countries, Papers

Friday, December 6, 2019

Basal Breast Cancer Samples for Students †MyAssignmenthelp.com

Question: Discuss about the Research on Basal Breast Cancer. Answer: Introduction This research was designed bearing in mind the increased cases and mortalities associated with breast cancer. More specifically is the basal like breast cancer in which the cancer cells move to distant tissues and make them different to treat. For instance, the breast cancer cells may move to the tissues where they metastasize and further form lesion on these tissues (Le et al., 2014). Research however indicates that the basal breast cancer cells depends on making alterations on both genetic as well as epigenetic mechanisms in order to complete the process of metastasis. This study was thus set up to find out whether targeting some genes can be important in the treatment of basal like breast cancer (Mavaddat et al., 2015). The interleukins are important in cell processes and thus are in significant numbers in cancer cells. The interleukins, for instance IL 3 is involved in cell growth, maturation and differentiation. More specifically, IL13R2 and IL13R1 compete for the binding to the ir receptors and can be used interchangeably. Previous gene profiling of IL13R2 indicated that this gene is abundant in lung metastasis but its role in cancer has not been clear (Papageorgis et al., 2015). As such, unbiased gene profiling using basal breast cancer was used to determine the roles of IL13R2 in metastasis. Methodology The major method used in this experiment was the gene expression profiling as well as the in silico leveraging of pre-existing breast tumor transcriptomes. In this case, the interleukin 13 receptor alpha 2 was knocked through the mediation of lentivirus. This was accompanied by imaging process which made use of bioluminescence to determine the role of this interleukin in breast cancer and metastasis in the lungs (Papageorgis et al., 2015). Further, confirmatory tests were carried out using microarrays and cell migration tests to better understand the molecular pathways which play part in basal breast cancer and lung metastasis. A weakness of this gene profiling method is that it is not possible to determine the roles of other genes like serpin B3, serpin B4 and CD36 which are also regulated by interleukin 13. Since this is a genetics approach, the biochemical methods which would have been used would be the Elisa tests. In this case, antibodies specific for the IL13R2 interleukin woul d be directed to specific sites in the breast and lung tissues. These would then be coupled with a secondary antibody which is specific for the breast cancers and the reaction measured via the spectrophotometer for either light absorbance or transmittance at a given wavelength. Results The authors were able to prove their hypothesis that when IL13R2 targets IL-13-STAT6-TP63, it alters the breast cancer metastasis. The authors in this research concluded that when there is an overexpression of the IL13R2 leads to increased metastasis in the lungs in some sunsets of basal like breast cancer. Moreover, for the first time, it has been discovered that there exists IL-13-STAT6-TP63 which is an antimigratory signaling molecule which can reduce the rate if metastasis in the breast cancer cells. The control experiment which was used in this research was the histology and immunochemistry in order to make confirmation of the results of microarray analysis on the role of IL13R2 in metastasis. It is this assumed that the IL13R2 can be used for therapeutic purposes to treat breast cancer (Papageorgis et al., 2015). This could be done by amplifying the gene coding for IL13R2 such that it leads to the increased expression of IL-13-STAT6-TP63 which in turn lowers the rate of metasta sis in the lungs and other tissues in patients suffering from breast cancer. The observed results could also be as a result of the orphan chemokine CXCL17 which is regulated by IL-3 genes and facilitates progression to cancer (Matsui et al., 2012). References Le, M. T., Hamar, P., Guo, C., Basar, E., Perdigo-Henriques, R., Balaj, L., Lieberman, J. (2014). miR-200containing extracellular vesicles promote breast cancer cell metastasis. The Journal of clinical investigation, 124(12), 5109. Matsui, A., Yokoo, H., Negishi, Y., Endo-Takahashi, Y., Chun, N. A., Kadouchi, I., ... Kobayashi, E. (2012). CXCL17 Expression by Tumor Cells Recruits CD11b+ Gr1highF4/80 Cells and Promotes Tumor Progression. PloS one, 7(8), e44080. Mavaddat, N., Pharoah, P. D., Michailidou, K., Tyrer, J., Brook, M. N., Bolla, M. K., ... Luben, R. (2015). Prediction of breast cancer risk based on profiling with common genetic variants. JNCI: Journal of the National Cancer Institute, 107(5). Papageorgis, P., Ozturk, S., Lambert, A. W., Neophytou, C. M., Tzatsos, A., Wong, C. K., ... Constantinou, A. I. (2015). Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis. Breast Cancer Research, 17(1), 98.

Friday, November 29, 2019

Copeland Baskin Essays (463 words) - Spirituality, Human Behavior

Copeland Baskin Mrs. Floyd Fitness Class 15 October 2017 Effects of Walking Walking is the easiest and most meditative exercise there is well other than yoga. However, walking is beneficial for fewer risks of bodily issues. Walking can bring people together in the time of need and for fun such as walking down the road, hiking, or just touring places. Today I a m going to be writing about walking, cycling, and yoga and its benefits on a person cognitively and with their multiple sclerosis. First , Multiple Scleroses is the hardening of cell tissue and with this disease, there is often cogitative impairment. According to Brian Sandroff , " Cognitive impairment is a highly prevalent, disabling, and poorly managed consequence of multiple sclerosis (MS). Upwards of 50% of MS patients demonstrate cognitive impairment based on neuropsychological testing " (209). With this being a fact, something has to be done to stop it. For example, exercise will helps with cognition in individuals by allowing them to have control of planning, coordination, inhibition, mental flexibility, working memory, and alertness. Walking allows one to have a peaceful mind and coordination because to walk well you have to focus on heel to toe, shoulders aligned, and arms swinging slightly with his/her movement. Cycling is helpful at really pumping up the heart rate. Secondly, yoga is excellent in coordination and control. Having coordination and control is very beneficial for the mindset and sclerosis. Meditation and deep breathing is one of the great things about yoga. Also, positions such as cat and cow, seated twist, child's pose, downward facing dog, supported forward bend, sun saltation, supported triangle pose, and seated warrior, helps with the relaxation of the muscle s with people having sclerosis, along with the concentrated breathing. Lastly, with all of the exercises combined, there was studies and experiments tested on people with relapsing multiple sclerosis and impaired cognition. According to Brian Sandroff , "improvements were made with walking, cycling, and yoga in quiet surroundings." (216). With this being said I think everyone should get out and exercise to prevent risks of diseases. In conclusion, walking, yoga, cycling, and basically any type of controlled exercise can help benefit one from diseases. It is all about managing, focusing, control, and breathing that really helps one's cogitative state. While yoga is more beneficial for relaxing the muscles for multiple sclerosis. Works Cited Sandroff , Brian M., et al. "Acute Effects of Walking, Cycling, and Yoga Exercise on Cognition in Persons with Relapsing-Remitting Multiple Sclerosis without Impaired Cognitive Processing Speed." Journal of Clinical Experimental Neuropsychology , vol. 37, no. 2, 15 Feb. 2015, pp. 209-219. EBSCO host , doi:10.1080/13803395.2014.1001723.

Monday, November 25, 2019

Copybloggers Best Advice On How To Scale To 8 Figures With Brian Clark

Copybloggers Best Advice On How To Scale To 8 Figures With Brian Clark If you are a marketer, then you have probably heard of Rainmaker Digital’s Copyblogger and read some of its articles. Copyblogger is one of the most iconic marketing blogs in the world. It is kind of a big deal, and there’s a good reason for that. The team at Copyblogger works hard to publish specific content that the audience finds extremely useful and valuable. Today, we’re talking to Brian Clark, founder and CEO of Rainmaker Digital and creator of Copyblogger. Brian and Copyblogger are recognized by many as the most influential blogging resources. If you haven’t got the hint yet, Brian knows his stuff! So, learn all about audience, value, and generosity from him. Getting back to basics with digital and content marketing automation and personalization; it’s still the human being in the middle of it that matters the most Know your audience for automation and personalization to be a delivery engine that gets better content to people who care about it Learn how to use new tools before applying them in the fundamentals of a sound digital marketing strategy; the tool does not make the strategy Audience First Content: Build your audience by providing them value; then you will understand what products they want and need Publish content first that attracts an audience, and then build a product Copyblogger is considered the Bible of content marketing despite no advertising Rainmakers: Use email marketing principles and have a product to sell to develop authority and clients How much to give away for free with your content marketing be generous, tell them everything, and share as much as you can, if you are selling something Content Creation to Revenue Generation: Are you getting more business than if you weren’t doing content marketing? Productize content and charge audience for information by knowing the objective and removing all objections that prevent buying Know your audience to determine the right format (audio, video, written, etc.) Internet is the greatest market research environment; it’s no longer about not having enough information, but how to manage and utilize it all Biggest mistake made is trying to appeal to everyone and not turn anyone off Links: Copyblogger Rainmaker Digital Brian Clark on Twitter Permission Marketing by Seth Godin Write and send a review to receive a care package If you liked today’s show, please subscribe on iTunes to The Actionable Marketing Podcast! The podcast is also available on SoundCloud, Stitcher, and Google Play. Quotes by Brian Clark:: â€Å"Be super generous because it’s competitive out there, and you have to find a way to stand out.† â€Å"It really should be the right content at the right time for the right person.† â€Å"Audience First is really the idea that you build that group of people by providing them value.† â€Å"That’s what we’ve done every time. Start with the content that attracts the audience, and then develop the products.†